Abstracts

The application of light and light-based technologies is now widespread in a significant number of human activities and leads to research in many technological areas. The development of photonic materials has not only revolutionized the area of Information and Communication Technology but has influenced widely in strategic global areas such as health, environment, lighting and energy. Our recent work on photonic and theranostic applications will be discussed, specifically, concerns about the synthesis and optical properties of rare earth doped nano and microstructured inorganic materials based on fluoride and oxides as theranostic agents for glioblastoma multiforme. Spheres, hollow spheres, cubes, rods, nanoparticles prepared by different methodologies will be presented, demonstrating high visible upconversion (UC) or near infrared (NIR) emission intensity after NIR excitation at transparent biological windows, radioluminescence, photoacustic features for multimodal imaging. In vitro assays of UC nanoparticles have been performed, and cell viability has been evaluated for gliobastoma cells, making them promising materials for bioimaging and photodynamic therapy using as an excitation source near infrared radiation. Ensemble and Single Particle were evaluated as primary nanothermometer with relatively high thermal sensitivity.References [1] L.F. Dos Santos, J.C. Martins, K.O. Lima, L.F.T. Gomes, M.T. De Melo, A.C. Tedesco, L. D. Carlos, R.A.S. Ferreira, R.R. Gonçalves. Physica B: Physics of Condensed Matter, 624, 413447, 1-11 (2022); [2] F. H. Borges, J. C. Martins, F. J. Caixeta, R. R. Pereira, L. D. Carlos, R. A. S. Ferreira, R. R. Gonçalves. Journal of Sol-Gel Science and Technology, 102, 249–263 (2022); [3] K. De O. Lima, L. F. Dos Santos, R. Galvão, A. C. Tedesco, L. De S. Menezes, R. R. Gonçalves. Frontiers in Chemistry 9, 1-13 (2021).